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王克华

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个人简介

硕士教授197911月出生,河南省周口市人

电子邮箱:khwang16@126.com

教育工作经历

2007年3月毕业于沈阳化工大学化学工艺专业,同年进入澳门大阳城集团2138网站首页化学系任化学专业教师

研究方向

1. 生物无机化学:设计和合成含功能性基团的铂、钌等金属配位化合物,并研究其抗癌活性和机理。

2.金属有机框架材料:通过水热合成技术合成和调控金属有机框架材料的结构及其荧光探针催化等性能

讲授课程

化工原理, 化工原理实验, 化工制图, 综合实验。

科研项目

1.新型无机抗肿瘤药物的合成及生物活性研究,鞍山市科技局科技计划项目(09SF23) 2009.07-2012.09, 主持, 已结题;

2.新型吸附材料多孔配位聚合物的设计、合成及其性能研究, 鞍山市科技局科技计划项目(2011MS36), 20011.07-2013.09, 主持,已结题;

3.杂多酸配合物合成及光催化降解有机染料污水研究, 鞍山市科技局科技计划项目(2014MS16), 20014.07-2016.09, 主持,已结题;

4.新型富勒烯衍生物化学稳定性及光学性质的理论研究, 辽宁省科技厅自然科学基金(2013020096), 2013.06-2015.06, 参与,已结项;

5. DNA插入基团的新型铂配合物合成及抗癌活性研究,辽宁省科技厅自然科学基金(20180550712), 2018.09-2022.09, 主持,已结项.

研究论文

1. Haifeng Yu*Kehua Wang, Xue Zhang,Wenju Wang. Complementary and Regioselective Synthesis of Isomeric 3-[Isoxazol-3(or5)-yl]indoles fromβ-Ethylthio-β-indolyl-α,β-unsaturated

Ketones, Synthesis, 2021, 53, 1989–1999.

2. Kehua Wang* , Mingchang Zhu, Shuang Ma, Xin Li, Meng Zhang, Enjun Gao.Three water soluble coordination polymers: synthesis, crystal structure and luminescent sensingfor Cr() and MnO4ions in the aqueous phase, Polyhedron, 2019, 166,60-64.

3. 彭程佳, 王克华*, 陆为学, 管纯倩, 胡雅静,马双,朱明昌,高恩君. 一个镍()配合物的合成、晶体结构及其与鲱鱼精DNA/BSA作用的光谱学研究, 光谱学与光谱分析, 2019, 39(2), 559-564.

4. Kehua Wang* . Synthesis, Crystal Structure, and Photoluminescent Properties of Two Porous Pillared-Layer Metal-Organic Frameworks Constructed by Benzene-1,3,5-Tricarboxylic Acid and Bisimidazole Ligands. Russian Journal of Coordination Chemistry, 2019, 45(5), 371–377.

5. Kehua Wang*, En-Jun Gao. Synthesis, crystal structure, DNA binding, molecular docking, cytotoxic activities and apoptosis of two copper (II) complexes constructed by 1,10-phen and semirigid bridge ligandsInorganica Chimica Acta2018, 482, 221–228.

6. Kehua Wang*.Three-pillared layer metal–organic frameworks assembled by imidazole-4,5-dicarboxylate and rigid bisimidazole ligands: synthesis, crystal structure, and sensing nitroaromaticsJournal of Coordination Chemistry2017, 70(24), 3982-3995.

7. Z. Wang, K. H. Wang*, L. J. Zhao, Y. Zhang, N. N. Chen, J. F. Zhao, F. Zhang, Y. Y. Shi. Two 2D Coordination Polymers Constructed from Rigid  bis(imidazoly) Ligands and Different Carboxylate: Synthesis, Crystal Structure and Photoluminescence Property. Koordinatsionnaya Khimiya, 2016,42(12) 751-757.

8. K.H. Wang*, M.-C. Zhu, D.-L. Wang, J. Bai,Y. Liu, G. Xin, T.-C. Li, D.-Y. Hou, and E.-J Gao. Solvothermal synthesis, crystal structure, and photoluminescent properties of two Cu() coordination polymers constructed by bisimidazole ligands. Journal of Structural Chemistry201556(1) ,191-196.

9. Kehua Wang*, En-Jun Gao. Recent advances in multinuclear complexes as potential anticancer and DNA binding agentsAnticancer Agents in Medical Chemistry, 2014,14, 147-169.

10. Kehua Wang*, En-Jun Gao. Synthesis, crystal structure, and characterization of two three fold interpenetrating Co() coordination polymers based on 1,4-benzenedicarboxylic acid and length modulated bisimidazole ligands. Journal of Coordination Chemistry, 2014, 67(4) , 563-571